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According to IIT Madras, the initiative aims to create the world’s largest collection of whole-human-brain 3D maps at cellular resolution.

Modi released C-STROKE, described by IIT Madras as the world’s first human ischemic stroke atlas. (Image: iitm.ac.in)
Prime Minister Narendra Modi launched a mission by the Sudha Gopalakrishnan Brain Centre (SGBC) at IIT Madras to create three-dimensional maps of more than 100 human brains at cellular resolution. The project will cover different stages of life, from the foetal stage to old age, and include brains affected by diseases.
According to IIT Madras, the initiative aims to create the world’s largest collection of whole-human-brain 3D maps at cellular resolution. The maps are expected to support research into brain development, neurological conditions and diseases, states the official press release.
The mission uses SGBC’s brain imaging technology to convert whole post-mortem human brains into detailed digital 3D maps. These maps will be made publicly accessible through an online platform, allowing researchers, medical professionals and clinicians worldwide to study brain structure and disease.
The project involves more than 200 researchers, engineers and technicians at SGBC, over 10 medical institutions across India, and more than 30 researchers from over 10 countries.
During the visit, Modi also released C-STROKE, described by IIT Madras as the world’s first human ischemic stroke atlas. Developed by SGBC, the open-access resource connects clinical MRI scans taken before death with microscopic images of the whole brain.
The atlas contains more than 1,000 annotated sections from a brain affected by stroke. It maps cellular markers linked to neuronal health, neuroinflammation, blood-brain barrier disruption, hypoxia and axonal injury. The resource is designed to help researchers understand how stroke-related changes visible in medical scans correspond to damage at the cellular level.
IIT Madras Develops the World’s First Human Ischemic Stroke AtlasDuring the Hon’ble Prime Minister Shri Narendra Modi’s visit to IIT Madras, Sudha Gopalakrishnan Brain Centre (SGBC) released C-STROKE, the world’s first human ischemic stroke atlas as an open global resource.This pioneering resource bridges clinical MRI scans with microscopic, whole-brain imaging, offering insights into stroke-related changes at the cellular level. Featuring over 1,000 annotated brain sections, the atlas maps key cellular markers associated with neuronal health, neuroinflammation, blood-brain barrier disruption, hypoxia and axonal injury.
Developed with support from IIT Madras Distinguished Alumnus Mr V. Prem Watsa, the atlas provides an open-access platform for researchers and clinicians worldwide to investigate cerebrovascular diseases and explore potential therapeutic targets.
C-STROKE represents a significant milestone in advancing understanding of stroke – https://t.co/TtOc385fcW
@iitmadras @kris_sg @BraincentreIITM @PMOIndia @narendramodi
#IITMadras #CSTROKE #StrokeResearch #Neuroscience #HealthcareInnovation
— IIT Madras (@iitmadras) October 14, 2026
The 3D maps were generated using the Param Shakti supercomputer, supported by the Ministry of Electronics and Information Technology (MeitY). The platform includes an open-access data viewer and analytical tools intended to help researchers investigate cerebrovascular diseases and identify potential therapeutic targets.
The C-STROKE project received support from V. Prem Watsa, an IIT Madras Distinguished Alumnus and chairman of Fairfax Financial.
Kris Gopalakrishnan, co-founder of Infosys and an IIT Madras Distinguished Alumnus who helped establish the centre and is a major donor, said the Prime Minister’s visit would inspire scientists working on the mission. He also expressed hope that it would encourage philanthropists to support and expand advanced scientific research in India.
Prof. Mohanasankar Sivaprakasam, head of SGBC at IIT Madras, said the mission brings together brain science, engineering, medicine and technology. He added that the maps and atlases could have significant implications for neuroscience and neuromedicine for decades to come.
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Prime Minister Narendra Modi launched a mission by the Sudha Gopalakrishnan Brain Centre at IIT Madras to create three-dimensional maps of more than 100 human brains at cellular resolution. The project covers all stages of life, from the foetal stage to old age, aiming to build the world’s largest collection of whole-human-brain 3D maps to support neuroscience research.
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